Group leader: PD Dr.-Ing. habil. Heidi Fleischer

Core competences include selective process knowledge as well as experiences in automation. Main goal is the transfer of manual procedures int automated processe. Main research topics include: 

Quality Control (Biotech, Food, Chemicals, Environmental)

An increasing market for automation solutions is the field of quality control in different application areas. In contrast to classical screening systems this field usually requires specialized proprietary solutions depending on the specific application. One important challenge is the use of different vials and arrays in one automation system.

The goal of the research activities is the transfer of manual processes into automated procedures with respect to all required regulations. Main part is the development of flexible and universal procedures which can be used for different applications. Application fields include quality control and innovative measurement technologies in chemical and pharmaceutical laboratories as well as an increasing automation of environmental analysis.

Catalysis and Organic Chemistry

The core competence of the project include homogenous catalysis, biocatalysis and organic synthesis with the goal of their transfer into automated systems and their use in combinatorial investigations. Main part of the research activities is the development of new homogenous palladium and iron catalysts for oxidative functionalization of lead structures, catalytic hydroaminomethylations for the synthesis of bioactive compounds and for the synthesis of new 5-HT-2A receptor antagonists.

High pressures (up to100 bar) in combination with high temperatures (up to 150°C), inert conditions and the use of different solvents are the main challenges for the development of suitable reaction systems. Additional reaction systems for use in automated heterogenous catalysis including the handling of solid materials are in the focus of the group.

Medicinal Chemistry & Forensics

Clinical laboratories have an increasing demand for automation solutions in order to reduce costs and make the processes more efficient. Whereas automated systems are available for the determination of single clinical parameters there is still the requirement of automation for the determination of complex clinical parameter using chromatographic and mass spectrometric measurement procedures including sample preparation, analysis and data processing.

 

 

CELISCA IS AN INITATIVE OF:

... and co-founded by State Mecklenburg-Vorpommern and national and international research organizations and companies
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18119 Rostock, Germany


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